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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Granulocytic Sarcoma | 1A0 Case 1 History
Case 1 History ---- This was the sixth SLCH admission for this 6 year old boy with acute monocytic leukemia. He was well until December 1978 when he was seen for easy bruisability. At that time he was diagnosed with acute lymphocytic leukemia and treated with Vincristine and Prednisone and, a month later, with cytoxan and asparaginase. In February 1979 he was readmitted with fever, malaise and hilar adenopathy. His fever resolved without any documented source. He also developed a rash after methicillin administration. He relapsed in June 1979 and was readmitted in July with thrush which was treated. Further chemotherapy was administered during an admission in August 1979. He was admitted again in October 1979 and the diagnosis was changed to AML after special bone marrow studies. WBC at that time was 382,000, mostly blasts. He was felt to be terminal and no further diagnostic or therapeutic measures were undertaken. He was discharged home but was readmitted as a terminal admission. He died in October 1979. ---- At autopsy the bone marrow was packed with immature cells and leukemic infiltrates were found in the brain, kidneys, lung, heart, liver and lymph nodes with small associated hemorrhages.
