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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Langerhans Cell Histiocytosis (LCH) | 10E LCH (Case 10) CD1a 1.jpg
The definitive stain in this case is CD1a, establishing these neoplastic cells as Langerhans histiocytes. (CD1a IHC) ---- Comment: The presence of clusters of atypical histiocytes in the suprasellar mass of a young adult is highly suspicious for a histiocytic neoplasm. Despite the fact that only a very small amount of lesional tissue was available for immunohistochemical workup, the presence of CD1a positivity is sensitive and specific for Langerhans cell histiocytosis.
