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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Langerhans Cell Histiocytosis (LCH) | 5B2 Langerhan's Cell Histiocytosis (LCH, Case 5) H&E 100X 1.jpg
The lesion is composed of a proliferation of histiocytic cells with reniform nuclei and nuclear grooves. Numerous admixed eosinophils are noted, some of which form 'eosinophilic microabscesses. ---- Ancillary findings (not shown): A CD1a immunostain is strongly positive in the histiocytic cells. An immunostain for BRAFV600E mutant protein is negative.
