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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Lymphoma, Intravascular Transforms to Primary | 2B3 Lymphoma, B cell (Case 1 -5 years later) area A CD20 20X
The tumor is a diffuse, large B-cell lymphoma (CD20 IHC) The lymphoma cells are negative for CD10 and only focally positive for Bcl-6 (5-10%). MUM-1 is positive in about 30% of the malignant cells. Overall this is consistent with a non-germinal center type B-cell lymphoma