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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Lymphoma, primary | 13B2 Lymphoma, primary CNS, B-cell (Case 13) H&E 3.jpg
The individual tumor cells are enlarged with irregular, notched hyperchromatic nuclei coarse chromatin; some with single or multiple prominent nucleoli and show marked pleomorphism. These cells have minimal to scant cytoplasm. There is abundant karyorrhectic/apoptotic debris. Mitotic figures, including atypical forms, are frequent. There is some reactive astrocytosis, and intermingled small lymphocytes and macrophages. (H&E)
