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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Plasmacytoma | 15A3 Myeloid sarcoma (looks like plasmacytoma) (Case 15) H&E 100X 2

Sections show sheets of intermediate to large cells with modest amounts of granular eosinophilic cytoplasm and eccentrically-located, immature appearing nuclei. Few mature granulocytes including band and segmented neutrophils are present. Lymphocytes are scarce. Tumor cells mimic plasma cells at low magnification but have significantly more granular cytoplasm.

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