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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Rosai-Dorfman Disease | 10A0 Case 10 History
Case 10 History (AANP DSS 2013 Case 8) ---- The patient was a 15 year-old African-American male with several months of progressively worsening headaches and confusion. He also had at least one seizure. Prior history was significant only for an “eosinophilic cellulitis” requiring systemic steroid therapy at some point in the past (no further details available). Preoperative MRI showed a 5.5 x 3.8 x 3.5 cm extra-axial enhancing mass along the right temporal lobe. Also noted was an enhancing defect of the ipsilateral mastoid bone extending to the scalp; it was unclear whether the two findings were related. Four months after undergoing a gross total resection of the mass, follow up MRI showed some residual lesion. Eighteen months after surgery, the lesion had regrown a little, but without mass effect or edema. Up until then seizures were well-controlled with medication, but in the ensuing six months the boy had some breakthrough seizures. No additional changes in the mass were noted as of the most recent imaging, nearly two years after initial resection. Material submitted: H&E stained slide of the mass.
