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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | Rosai-Dorfman Disease | 6B7 Rosai-Dorfman (Case 6) H&E 8.jpg
The neurosurgical specimen showing a lesion composed of sheets of large pale histiocytic cells with vacuolated, eosinophilic cytoplasm accompanied by scattered lymphocytes and plasma cells. Focal, well-preserved emperipoletic lymphocytes within the cytoplasm of histiocytes are numerous. (H&E)