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Washington University Experience | NEOPLASMS (MENINGIOMA) | Anaplastic | 15B3 Meningioma, anaplastic (Case 15) H&E 1.jpg
The tumor is composed of a high-grade spindled cell neoplasm with a predominantly sheet-like growth architecture. The tumor shows areas of hypercellularity and patchy areas of 'small cell' change. Mitotic figures were 23-24 mitoses/10HPF in several sampled regions. There is invasion of the tumor into the overlying bone.