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Washington University Experience | NEOPLASMS (MENINGIOMA) | Anaplastic | 23B1 Meningioma, anaplastic (Case 23) B4 H&E 20X
23B1-4 This is a poorly differentiated malignant neoplasm with prominent papillary to pseudopapillary architecture and large areas of associated hemorrhage. The tumor cells have abundant eosinophilic cytoplasm with marked pleomorphism; the nuclei are vesicular with most of them containing macronucleoli. An occasional nucleus has intranuclear cytoplasmic pseudo-inclusions. Mitoses are frequent and the count, focally, reaches up to 24/10HPF.
