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Washington University Experience | NEOPLASMS (MENINGIOMA) | Anaplastic | 2C3 Meningioma, anaplastic (Case 2) 1 H&E island right edge 40X
2C3-5 The tumor grows in multiple patterns. The first pattern consists of cells having a sheet-like epithelioid appearance, some in whorls. Some tumor cells have abundant eosinophilic cytoplasm, exhibit severe pleomorphism including some bizarre forms and have prominent nucleoli. In places there is brisk mitotic activity reaching up to 17/10 HPF and histologically resemble frank carcinoma. Numerous tiny foci of necrosis are also notable.
