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Washington University Experience | NEOPLASMS (MENINGIOMA) | Anaplastic | 6A2 Meningioma, anaplastic (Case 6) H&E 4
This meningothelial neoplasm exhibits multiple growth patterns, including whorl formation and fascicular growth featuring herringbone and pseudo-Verocay growth patterns. Mitotic activity is high (>23 mitoses/10HPF). The tumor shows focal brain invasion, sheeting architecture, macronucleoli, large areas of spontaneous necrosis, and hypercellularity. (H&E)