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Washington University Experience | NEOPLASMS (MENINGIOMA) | Chordoid | 1F3 Meningioma, anaplastic, chordoid (Case 1) A8 GFAP 20X
Areas of brain invasion are highlighted by GFAP immunohistochemistry. (GFAP IHC) ---- The morphology, immunophenotype, and finding of elevated mitotic rate of more than 20/HPF are diagnostic of an anaplastic meningioma (WHO grade 3). Given the history of anaplastic meningioma s/p multiple resections this is best classified as residual/recurrent.