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Washington University Experience | NEOPLASMS (MENINGIOMA) | Chordoid | 4B1 Meningioma, chordoid (Case 4) H&E 1.jpg
4B1-4 The tumor consists of a neoplastic proliferation characterized by spindled cells arranged in ribbon and cord-like structures, with abundant basophilic mucin. Elsewhere, the tumor shows more conventional meningothelial morphology where tumor cells are arranged in small whorls and nests, but the predominant morphology is that of a cord-like architecture with basophilic mucin in the surrounding stroma. The tumor cells are characterized by moderate amount of eosinophilic cytoplasm arranged in spindled and more epithelioid forms, ovoid, frequently irregular nuclei with occasional nucleoli as seen using a 40x objective, nuclear grooves, and rare intranuclear inclusions and nuclear clearing. The chromatin is generally finely dispersed. Mitotic activity and necrosis are not identified. (H&E)
