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Washington University Experience | NEOPLASMS (MENINGIOMA) | Gross Pathology | 36 Meningioma (Case 36) Gross_1

Case 36 History ---- This 82 year old patient developed asymmetric rigidity, bradykinesia, resting tremor and poor balance with no eye movement problems but had only modest benefit from relatively high dose of levodopa. She had an MRI of the brain 4 years prior to death that revealed a lesion consistent with a meningioma and this was not further explored or treated. She developed mild cognitive impairment and then much more cognitive impairment with marked dementia. Hallucinations and suspicious thinking became increasingly problematic. ---- At autopsy the fresh brain weighed 1161g. A diagnosis of Diffuse Lewy body disease and Alzheimer’s disease was established. ---- 36A The image shows a dissected meningioma adjacent to its location in the left frontal lobe (WHO Grade I).

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