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Washington University Experience | NEOPLASMS (MENINGIOMA) | Papillary | 2A2 Meningioma, papillary (Case 2) H&E 3 (2).jpg
2A2-6 Sections reveal a hypercellular, epithelioid neoplasm, with the majority of tumor cells containing round to oval nuclei and abundant eosinophilic cytoplasm. Many of the nuclei have clear holes and nuclear pseudoinclusions. The tumor grows mostly in sheets and nodules, focally showing a papillary pattern. Additionally, there are prominent perivascular structures with nuclear free zones resembling the perivascular pseudorosettes seen in ependymomas. Focal areas show small cell features. Scattered mitotic figures are seen, reaching up to 8/10HPF with focal necrosis.