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Washington University Experience | NEOPLASMS (MENINGIOMA) | Psammomatous | 6B4 Meningioma, unusual psammoma bodies (Case 6) H&E 2.jpg
There are abundant collagenous bundles with calcified cores along with some more traditional round psammomatous calcifications. The tumor cells intervene between these psammomatous calcifications and in general have a solid growth pattern with some lobular appearance. ---- Not shown: Immunohistochemistry shows that rare tumor nuclei show faint positivity for progesterone receptor (PR). The proliferation marker Ki67 stains a very low subset of tumor cell nuclei at variable density, found overall at <1% of total tumor nuclei. The histomorphologic and immunophenotypic characteristics are those of a Meningioma, psammomatous variant, WHO Grade I.
