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Washington University Experience | NEOPLASMS (MESENCHYMAL, NON-MENINGOTHELIAL) | Chordoma | 14A1 Chordoma, chondroid (AANP 1981, Case 2) H&E X1 2
Case 14 History (AANP 1981, Case 2) ---- The patient was a 50 year old alcoholic female with a 15 year history of progressive headaches. A left 6th nerve palsy was noted 12 years ago. Since that time, she has had progressive left-sided proptosis, diminution of vision, and recurrent episodes of epistaxis. Recent skull x-rays demonstrate a large tumor destroying the clivus, extending to form a mass in the left middle fossa, opacifying all left-sided sinuses and extending into the retropharynx. Subtotal excision was performed (9/79) yielding 35 gm. of gray, gelatinous tumor. The patient underwent post-operative radiation therapy and was alive at last follow-up. ---- 14A1-3 Multiple sections of tumor consist of a largely cartilaginous pattern with little atypia or mitotic activity. Other areas showed a more chordoma like pattern. (H&E)
