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Washington University Experience | NEOPLASMS (MESENCHYMAL, NON-MENINGOTHELIAL) | Chordoma | 4B1 Chordoma, sacral (Case 4) H&E 8.jpg
4B1,2 Histologic evaluation of the sacral lesion shows a large lobulated tumor composed of epithelioid cells with bland nuclei and abundant cytoplasm. Some have bubble-like vacuolated cytoplasm and arrange in cords or rows against mucoid stroma. The tumor cells invade into bone in multiple foci. (H&E)
