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Washington University Experience | NEURODEGENERATION | ALS | 1E2 ALS (Case 1) N18-19 Precentral gyrus TDP43 3
The precentral gyrus shows scattered TDP43 immunoreactive cytoplasmic skein-like inclusions. There is some fibrillary material within the cytoplasm of rare, scattered oligodendrocytes. ---- Not shown: Bielschowsky stained material does not show Alzheimer senile plaques and neurofibrillary tangles.