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Washington University Experience | NEURODEGENERATION | ALS | 3B5 ALS, precentral gyrus atrophy (Case 3) N15 precentral TDP43 60X
A rare atrophic neuron in the precentral gyrus contains a TDP43 immunopositive skein-like inclusion. Immunohistochemistry for transactive response DNA binding protein 43 kDa (TDP43) is negative in the non-primary motor cortices. (TDP43 IHC)