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Washington University Experience | NEURODEGENERATION | Argyrophilic Grain Disease (AGD) | 4A3 Argyrophilic Grain Dementia & Hippocampal sclerosis (Case 4) PHF1 WM 40X

4A3 Argyrophilic Grain Dementia & Hippocampal sclerosis (Case 4) PHF1 WM 40X
Glial inclusions were patchy in the white matter. (PHF IHC) ---- Not shown: There is severe neuronal loss and astrocytosis in part of the hippocampal CA1 and CA4 subfields of the hippocampus and subiculum, consistent with hippocampal sclerosis. There are no parenchymal beta-amyloid deposits or amyloid angiopathy; no neuritic plaques are present. No Pick bodies or Lewy bodies are seen.



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