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Washington University Experience | NEURODEGENERATION | Argyrophilic Grain Disease (AGD) | 6B5 Argyrophilic grains, AGD, entorhinal cortex (Case 6) PHF 7
Tau immunohistochemistry also reveals some tau-immunoreactive astrocytic processes and coiled bodies; tau grains are best appreciated in the entorhinal cortex. Frequent tangles are appreciated in the entorhinal cortex, which also has neuronal loss and gliosis.