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Washington University Experience | NEURODEGENERATION | Corticobasal Degeneration (CBD) | 1F1 CBD (Case 1) L9 SN PHF1 40X
Neurons and glia in the substantia nigra show numerous inclusions in residual viable elements. The substantia nigra is markedly depopulated in neurons, contains free and macrophage engulfed pigment, and is accompanied by numerous astrocytes. Lewy bodies are not present. (PHF1 IHC)
