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Washington University Experience | NEURODEGENERATION | Corticobasal Degeneration (CBD) | 2B12 CBD (Case 2) SN L9 H&E 20X 2
Low magnification image of the substantia nigra shows marked depletion of neurons. In some cases the apparent grossly visible pigmentation of the substantia nigra is contributed by loss of pigment into the neuropil and macrophages. (H&E)