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Washington University Experience | NEURODEGENERATION | Corticobasal Degeneration (CBD) | 6C6 CBD (Case 6) L11 60X 1
The residual neurons in the substantia nigra in CBD only occasionally have such prominent skein-like tangles which are more typical of subcortical involvement in Alzheimer disease and classical tangles of Progressive Supranuclear Palsy (PSP). (H&E)