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Washington University Experience | NEURODEGENERATION | Hippocampal Sclerosis of Aging | 5A0 Case 5 History

5A0 Case 5 History
Case 5 History ---- The patient was 91 years old when she was first evaluated in 2014. The family gave a history of two years of cognitive decline. She had amnestic memory loss but it appeared somewhat rapid given the difficulty in forgetting and recognizing family members. She had weight loss at this time and some irritability. However, her language skills were intact and she continued to be organized in her house. There is an old history of head trauma. At the age of 93 years there was continued decline in episodic or short-term memory and further decline in activities of daily living. Her CDR rating had declined to 1 or mild dementia, her psychometric profile had declined and again a non-focal neurological exam was noted. The clinical diagnosis remained AD and Lexapro was started for agitation and behavioral problems. The patient was lost to follow up and was admitted to hospice apparently for head and neck (tongue) cancer which was diagnosed in September of 2011 as moderately differentiated squamous cell carcinoma, keratinizing type. The patient died in July 2016.



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