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Washington University Experience | NEURODEGENERATION | Huntington Disease | 14C2 Huntington's Disease (Case 14) L6 H&E 2X scale
The caudate nucleus and putamen show marked neuronal loss – the caudate nucleus is more severely affected than the putamen - astrocytosis, rarefaction, and microvacuolation. The pencil fibers are pale in many areas. (H&E)