Table of Contents
Washington University Experience | NEURODEGENERATION | Huntington Disease | 1E Huntington's Dz (Case 1) GFAP whole mount
GFAP is increased in the basal ganglia, particularly in the caudate, as patches. (GFAP IHC) ---- Not shown: The pons shows atrophic and decreased number of neurons in the basis pontis. The crossing and descending fiber tracts are unremarkable. ---- Neuro Final Diagnosis: Huntington's Disease ---- Neuro Diagnosis Comment: The constellation of findings confirmed the clinically diagnosed Huntington disease, which is also strongly supported by the genetic test that showed 17 and 43 CAG repeats of her Huntingtin alleles.
