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Washington University Experience | NEURODEGENERATION | Huntington Disease | 7A2 Huntington's Dz (Case 7)
Coronal sections of the right cerebral hemisphere confirm the significant degree of cortical atrophy involving the frontal lobes and parietal lobes. The deep gray nuclei are remarkable for an almost total collapse of the head of the caudate nucleus which appears as a thin orange-stained band in the lateral aspect of the extensively dilated lateral ventricle. The superior and anterior aspect of the caudate head are most extensively involved; the inferior aspect merging into the substantia innominata appears less extensively involved. The normal convex outlines of the head of the caudate are now concave. Adjacent areas of the internal capsule appear unremarkable.
