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Washington University Experience | NEURODEGENERATION | Infantile Neuroaxonal Dystrophy (INAD) | 2G1 INAD (Seitelberger Dz, Case 2) 1 DRG 20X
Sections of dorsal root ganglia (DRG) in the lumbar region showed a relatively well-preserved neuronal population with occasional nodules of Nageotte, evidence of neuronal degeneration. The dorsal root ganglia themselves were essentially free of spheroids, not unexpected since dystrophic swellings form at synapses and terminal axons which DRG lack. (H&E)
