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Washington University Experience | NEURODEGENERATION | Lewy Body Disease (LBD) | 2 LBD - Gross Pathology - Cerebrum LBD -Dementia | 14A6 PD & DLBD (pure) (Case 14) 6

14A6 PD & DLBD (pure) (Case 14) 6
The brainstem has been sectioned to show pallor of the midbrain substantia nigra and pontine locus ceruleus. ---- Final Neuropathologic Diagnoses: No AD by any criteria (amyloid-beta entirely absent); Dementia with Lewy bodies (DLB), neocortical, limbic and brainstem Lewy bodies and Lewy neurites. ---- This case is an excellent example of pure DLB with no hint of AD except for medial temporal tangles in an aging-associated distribution.



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