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Washington University Experience | NEURODEGENERATION | Lewy Body Disease (LBD) | 3 LBD - Gross Pathology - Pallidotomy and DBS | 1A0 Case 1 History
Case 1 History ---- The patient was a 61yo male whose symptoms began at age 35, diagnosed as PD at 37yo. Medication was initiated but symptoms became intractable. Subsequently, he was treated surgically with left pallidotomy and then bilateral subthalamic nuclei stimulator placement in August 2000 which resulted in significant improvement in his symptoms. MRI of the brain in 2003 revealed an old left putamen scar, periventricular white matter foci of hyperintensity seen on T2 weighted images and bilateral subthalamic electrodes in good position. Lower extremity tingling (L>R) and unsteady gait resulted in a diagnosis of cervical spondylosis. A C3-C6 laminectomy was complicated by post-operative quadriparesis. Emergent re-exploration did not demonstrate a hematoma. Myelogram did not reveal an etiology. He recovered well and was discharged to rehab. He continued to have weakness of all extremities (L>R) which improved gradually over the next 2 weeks. He was found unresponsive in October 2003 and CPR was unsuccessful.
