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Washington University Experience | NEURODEGENERATION | Lewy Body Disease (LBD) | 3 LBD - Gross Pathology - Pallidotomy and DBS | 2B Case 2 Denouement
Neuro Final Diagnosis: Idiopathic (Lewy body) Parkinson's disease; Necrosis, globus pallidus, left (Hx pallidotomy, 1996) ---- Not shown: Silver staining shows a few neurofibrillary tangles and rare neuritic plaques in the entorhinal cortex and frontal cortex, however, the number is very low and a diagnosis of Alzheimer's disease is not warranted. Microscopic examination shows marked neuronal loss, gliosis and Lewy bodies in the substantia nigra and locus ceruleus.
