Table of Contents
Washington University Experience | NEURODEGENERATION | Lewy Body Disease (LBD) | 4 LBD - Gross Pathology - LBD-Dementia with AD | 13A0 Case 13 History
Case 13 History ---- The patient was an 85yo female with a history of stage III idiopathic parkinsonism for 14 years. Her past medical history was also significant for myocardial infarction in 1985, followed by a five vessel bypass surgery, aortic stenosis, hypertension/hypotension, an esophageal problem, and diarrhea (frequent, 3-4 times a day without blood, mucus or melena). Her parkinsonian symptoms were increased rigidity, bradykinesia, akinesia, resting tremor, and chorea. She had moderately stooped posture and walked with difficulty. Turning had moderate hesitation. In December 1997, she was admitted because of decreased mental status and seizure-like shaking without loss of consciousness. The principal secondary diagnoses were delirium and segmental myoclonus at that time. None of the episodes had the clinical EEG characteristics of epileptic seizures, mostly repetitive irregular myoclonus without EEG change. MRI findings of brain were unremarkable. In January her feces were positive for clostridium difficile toxin. In February 1998 a chest radiograph showed left lower lobe infiltrate. She expired in February 1998.
