Table of Contents
Washington University Experience | NEURODEGENERATION | Lewy Body Disease (LBD) | 4 LBD - Gross Pathology - LBD-Dementia with AD | 5A0 Case 5 History
Case 5 History ---- The patient was a 72yo female who had been admitted to a nursing home in 1987 with diagnoses of Parkinson's Disease, depression, and status-post fracture of left shoulder. Signs of PD began in 1984 with a typical shuffling gait and small handwriting. Her symptoms were improved with Symmetrel or Sinemet. She was treated as an outpatient until 1987 when she suffered a major depressive episode requiring electro-convulsive therapy. Upon discharge from JH, she was admitted to a nursing home. She continued to show signs of delusion but this gradually decreased. She showed initial signs of dementia including poor memory for recent events. A CT scan around that time showed an interval increase in diffuse cerebral atrophy. By June 1993, she rated CDR-2 (moderate dementia). She was disoriented to time and place. There was impairment of language, fund of knowledge, arithmetic ability, and social interaction. She was felt to have nocturnal hallucinations or confusion. She suddenly died in September 1993.
