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Washington University Experience | NEURODEGENERATION | Lewy Body Disease (LBD) | 4 LBD - Gross Pathology - LBD-Dementia with AD | 8A0 Case 8 History
Case 8 History ---- The patient was an 81yo female with a history of parkinsonism manifesting in 1982 and diagnosed in 1983. She was treated with various drug regimens; however, the disease was progressive with loss of ambulatory function and development of urinary incontinence requiring an indwelling Foley catheter. There was also progressive cognitive decline. In 1986 she fractured her right hip and in 1987 injured her left knee, both times requiring surgical repair. By 1988, she was wheelchair dependent. The patient's course was complicated by several episodes of aspiration pneumonia and by dysphagia. In May of 1990, a gastrostomy tube was placed. In December of 1993 she was admitted to an OSH with tachypnea, fever, and suspected recurrent aspiration pneumonia. There was also drainage exuding from the gastrostomy tube site. The patient was admitted to the ICU. Cultures of blood, tracheal aspirate, and the gastrostomy site drainage were obtained and the patient was begun on intravenous antibiotic therapy (Zinacef). However, her fever increased to 106oF and she experienced generalized deterioration. The patient expired in December of 1993.