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Washington University Experience | NEURODEGENERATION | Multiple Systems Atrophy (MSA) | 16D1 MSA (Case 16) psyn L11 40X
16D1-6 Neuronal loss and gliosis are mild in the tegmentum but more marked in the basis pontis. White matter tracts and nuclei have severe alpha-synuclein pathology, manifested by numerous GCIs, scattered neuronal cytoplasmic (NCIs), neuronal intranuclear inclusions (NIIs), and neuropil threads or neurites. (pSYN IHC)