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Washington University Experience | NEURODEGENERATION | Multiple Systems Atrophy (MSA) | 6G MSA (Case 6) Purkinge cell preservation H&E 1.jpg
There is neuronal loss in the Purkinje cell layer and in the dentate nucleus. The deep white matter shows axonopathy, gliosis, and numerous GCIs. GCIs are also noted in lesser numbers within the granule cell and Purkinje cell layers.