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Washington University Experience | NEURODEGENERATION | Multiple Systems Atrophy (MSA) | 8C1 Multiple system atrophy (MSA, Case 8) Pons H&E whole mount
8C1,2 Neuronal loss and gliosis are severe in the tegmentum, including the locus coeruleus and very severe in the basis pontis. White matter tracts and nuclei have severe alpha-synuclein pathology, manifested by numerous GCIs. (H&E)