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Washington University Experience | NEURODEGENERATION | NBIA1 (PKAN, Hallervorden-Spatz Dz) | 5A1 Hallervorden-Spatz Dz (NBIA, Case 5) A1
5A1-4 At autopsy the weight of the unfixed brain was 1330g. Coronal sections of the cerebral hemispheres revealed a somewhat atrophic cortical ribbon, underlying white matter, basal ganglia, and thalamus. The ventricular system was markedly dilated with blunting. The substantia nigra showed pigment loss and orange discoloration.