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Washington University Experience | NEURODEGENERATION | Pick Disease | 10A3 Pick Dz (Case 10) 9
10A3,4 Coronal sections of the cerebral hemispheres reveal the anterior temporal lobe is markedly atrophic, demonstrating a paper-thin cortex. The subcortical white matter and that of the centrum semiovale are reduced in volume and the mid-portion of the corpus callosum is particularly thin. The lateral ventricles show expansion and blunting of their angles.