Table of Contents
Washington University Experience | NEURODEGENERATION | Primary Age-Related Tauopathy (PART) | 2A0 Case 2 History
Case 2 History ---- At age 76, in January 2006, she was evaluated in the Memory and Aging Project (MAP) at the Knight Alzheimer Disease Research Center. The patient had a family history of dementia in that her father became demented at age 72 years and two of her five siblings also were affected with dementia beginning at ages 75 and 76 years. She was medically stable but carried the diagnoses of hypertension, glaucoma, and gastroesophageal reflux disorder; and a history of malaria contracted in Africa. A collateral source suggested the patient had “inconsistent” forgetfulness over many years that was non-progressive and did not affect her daily function. She was rated CDR 0. From 2007-2013 she was “always absent-minded” but functioned at her usual level. At each of those assessments, she was rated a CDR 0. Subsequent to her T8 assessment, she developed metastatic renal cancer. She worked up until the time of her terminal illness when she entered hospice. She died a few weeks later at age 85 years. The retrospective postmortem dementia interview yielded a CDR score of 0. She was cognitively normal at all times of Memory and Aging Project assessment and up until her terminal illness. The clinical cause of death was inanition.
