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Washington University Experience | NEURODEGENERATION | Progressive Supranuclear Palsy (PSP) | 12B2 PSP (Case 12) N10 dentate (grumose degeneration) H&E 10
12B2,3 A section of the cerebellum shows relative preservation of Purkinje and granule cells. There is significant neuronal loss, astrogliosis, and eosinophilic granular aggregates around neurons (“grumose degeneration”) in the dentate nucleus (H&E)
