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Washington University Experience | NEURODEGENERATION | Progressive Supranuclear Palsy (PSP) | 15A0 Case 15 History - Copy

15A0 Case 15 History - Copy
Case 15 History ---- The patient was a 73yo female with a long-standing clinical history of progressive supranuclear palsy who presented seven years prior to death with gait unsteadiness and a tendency to fall. The patient was seen at the Mayo clinic in 1989 and was given the diagnosis of progressive supranuclear palsy (PSP) based on clinical examination. The patient had gradually worsening gaze palsy, four limb and trunk stiffness and gait unsteadiness. In later years she had difficulty with speech and swallowing. Her swallowing difficulty progressed to the point of placement of a gastrostomy tube 5/1993 at Barnes Hospital without complication. In addition, she had a history of significant hypertension treated with antihypertensive medication prior to her diagnosis of PSP. She had not taken antihypertensive medication for several years prior to her death. The patient expired at home in 2/95. Her general autopsy showed that acute bilateral bronchopneumonia was the immediate cause of death. Past medical history had only been remarkable for a right breast mass treated with lumpectomy.



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