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Washington University Experience | NEURODEGENERATION | Progressive Supranuclear Palsy (PSP) | 3A3 PSP (Case 3) ION H&E 2

3A3,4 The inferior olivary nucleus (ION) has many swollen and vacuolated neurons with bizarre hypertrophic astrocytes consistent with inferior olivary hypertrophy, a transneuronal effect. There was also severe pathology in the red nucleus and the dentate nucleus which are connected to ION by the Guillain Mollaret triangle.

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