Table of Contents
Washington University Experience | NEURODEGENERATION | Progressive Supranuclear Palsy (PSP) | 9B10 PSP (Case 9) L12 ION H&E 40X 2
9B10,11 Involvement of the nuclei comprising the triangle of Guillain and Mollaret, also known as the dentato-rubro-olivary pathway, (red nucleus, contralateral dentate nucleus, ION) occasionally produce an unusual transneuronal hypertrophic vacuolating change in the neurons of the ION. Several vacuolated neurons are accompanied by markedly abnormal astrocytes. (H&E)