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Washington University Experience | NORMAL | Clarke's column | 1A2 Clarke's Column Nucleus chromatolysis mimic (Case 1) H&E 2
1A2,3 Higher magnification image of adult human Clarke’s column neurons show Nissl substance marginated around the cytoplasmic periphery of the cell body. Although Clarke’s column neurons have a superficial resemblance to central chromatolysis, the neuronal cell body response to axonal crush injury, they typically have a more granular appearance in contrast to the glassy cytoplasm of central chromatolysis.
