Table of Contents
Washington University Experience | PERIPHERAL NEUROPATHY | 16 DIABETIC NEUROPATHY | 3 Sympathetic Autonomic Neuropathy | 1A0 INTRODUCTION
Introduction ---- The following cases are derived from a large autopsy study in which details of individuals diabetes (age of onset, severity, treatment history and HbA1c levels, response to therapy, electrophysiology and autonomic function) were surprisingly minimally or incompletely known. Therefore, I will not present even rudimentary histories in this section. My prediction is that the pathology to be described is more substantive than a pathologic curiosity and that where neuroaxonal dystrophy occurs there is typically pathophysiology. Many diseases exhibit synaptic pathology; however, it is harder to characterize and quantitate than neuronal loss. See the neuroaxonal dystrophy entry in this atlas in the BASIC PROCESSES section and the Infantile Neuroaxonal Dystrophy (Seitelberger’s disease) entry in the NEURODEGENERATION section.
