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Washington University Experience | PERIPHERAL NEUROPATHY | 6 AXONAL DEMYELINATION (BASIC PROCESS) | 1A1 Image - Teased
Case 1 No History 1A1,2 Lengths of individual lightly fixed, osmicated myelinated axons can be dissected or "teased" out of a fascicle. Each myelin internode, maintained by a single Schwann cell, ranges from 0.2 to 1.8 mm on axons of different sizes. Internode length increases linearly with axon diameter as shown in this image. (teased fiber preparation). Active demyelination or axonal degeneration is readily identified as well as evidence of previous degenerative or demyelinative-remyelinative episodes.
